Sherif El-Refai is an ambitious medical professional who recently established his career as a pharmacist in Jersey City. Trained and educated as a pharmacist, Sherif El-Refai has build a background with a graduate degree in business. He recently attended the University of Florida, where he earned a Master of Business Administration that focused on global management, marketing, and competitive strategy.
Besides committing to understand all the aspects of pharmacy, Sherif El-Refai gained experience in developing and submitting Business plans that incorporated pharmacy services into pre existing medical departments. He even completed independent research for the American Journal of Health-System Pharmacists and gained experience to hold a position of pharmacist from 2011-2012.
Since his earning as Doctor of Pharmacy at the University of North Carolina at Chapel hill (UNC-CH) in 2011, Sherif El-Refai gained professional experience in his role as pharmacist in Jersey City. As a UNC_CH student, Sherif El-Refai maintained a dean’s listing distinction, remarkably gaining determination to the National Society of Collegiate Scholars. Additionally he served as a member of the Clinical Discussion Group of Muslim Student Association.
Sherif El-Refai further initiated his UNC-CH research in 2005, where he finished his Bachelor of Science in Pharmaceutical Sciences and then later worked towards a doctorate on the Eshelman School of Pharmacy. During his course he received diverse professional experience serving as a Pharmacy Technician with Eckerd’s Pharmacy from 2006 to 2007.
Sherif El-Refai undertook numerous clerkships during his course of studies, initially completing his Introductory Hospital Experience Rotation at WakeMed Hospitals in Raleigh in 2008 where he subsequently finished his clerkships in the diverse practice areas of hematology/oncology, ambulatory care, inpatient remedy, and ICU trauma.
Sherif El-Refai even contributed to the advancement of his field through numerous research and by writing projects. Collaborating with his pharmacy supervisor, he researched and composed pamphlet for patients titled as “Daily Training Regimen for the Elderly.” he also created brochures on”Medication Therapy Management Services” and gave a presentation discussing the benefits of community partnerships.
With a doctor of pharmacy from the University of North Carolina at Chapel Hill, Sherif El-Refai is now working to earn a PhD in pharmaceutical sciences from the University of Kentucky. As a pharmacist Sherif El-Refai conducts lung cancer research and serves as an oncology pharmacist at the Black Lab, University of Kentucky’s Markey Cancer Center.
Lung cancer is the leading cause of cancer worldwide.The major two forms of lung cancer are nonsmall cell lung cancer (NSCLC=85%) of lung cancer and small-cell lung cancer (SCLC=15%). Despite recent advances in the management of resected lung cancer tumors and more effective treatments in the metastatic setting, the cure rate of lung cancer remains low. Successful molecular testing of lung cancer requires the identification and understanding of events that takes place during the multistep tumorigenic process of lung cancer. As with other solid tumors, lung cancer is the result of the accumulation of genetic and epigenetic alterations over a long course of exposure to a carcinogen.
Discovering new prognostic or predictive biomarkers or developing new detection tools for lung cancer is one of the major areas of transitional cancer research. However, given our current understanding of the multifactorial process of lung carcinogenesis and hetrogeneous nature of the disease, monitoring of one or a few genes is limited. A pangenomic analysis seems more efficient for deciphering the complexity of lung cancer. The prospect of identifying specific events in lung carcinogenesis is significantly brightened by the recent development of high-throughput gene expression analysis.
Sherif El-Refai further tried to understand Gene expression, a biological process at the cellular level involves the conversion of DNA information into molecules such as proteins. The process that allowed the cells to adjust to their surroundings by controlling when and how many proteins are to be produced. The gene expression includes two stages: transcription and translation. During transcription, DNA information is copied to produce messenger RNA, which carries the information to protein-producing ribosomes in the cell. Carrier molecules read this information during the translation stage, and ribosomes use it to form a new protein.
Holding several advanced degrees in the area of pharmaceutical sciences, Sherif El-Refai devoted nearly 10 years of study to the eradication of cancer. In addition to serving in the University of Kanas College of Pharmacy Black Lab, where he conducted lung cancer research to assist in developing more efficient treatments, Sherif El-Refai serves the Markey Cancer Center in the position of oncology pharmacist.
In the study of lung cancer, several subsets of the disease exit. Researchers say that because of the existence of these multiple subsets, the approach of treating the disease should vary for each patient based on which subset their cancer falls into.
Cancer of the lung, like all cancers, results from an abnormality in the body’s basic unit of life, the cell. Normally, the body maintains a system of checks and balances on cell growth so that cells divide to produce new cells only when new cells are needed. Disruption of this system of checks and balances on cell growth results in an uncontrolled division and proliferation of cells that eventually forms a mass known as tumor.
Tumors can be benign or malignant; when we speak of “cancer,” we refer to those tumors that are malignant. Benign tumors usually can be removed and do not spread to other parts of the body. Malignanttumors, on the other hand, often grow aggressively locally where they start, but tumor cells also can enter into the bloodstream or lymphatic system and then spread to other sites in the body. This process of spread is termed metastasis; the areas of tumor growth at these distant sites are called metastases.
Since lung cancer tends to spread or metastasize very early after it forms, it is a very life-threatening cancer and one of the most difficult cancers to treat. While lung cancer can spread to any organ in the body, certain locations — particularly the adrenal glands, liver, brain, and bones — are the most common sites for lung cancer metastasis. By knowing the makeup of each subset and how they react to each type of therapy, the research will aid in improving patient outcomes.
Sherif El-Refai is an accomplished researcher and pharmacist who holds a PhD from the University of North Carolina at Chapel Hill and has even pursued his MBA from the University of Florida. When it comes to the level of proficiency in the field of pharmacy, Sherif El-Refai is committed to understanding all the aspects of the practice and has experience in developing and submitting business plans that incorporate pharmacy services into pre-existing medical departments. He holds certification in pharmacy-based immunization delivery; basic life support; and advanced cardiac life support, anticoagulation, hypertension and lipids, and diabetes.
As a pharmacist in Jersey City, Sherif El-Refai persued a particular interest in the treatment of cancer. A writer and presenter on the topic, Sherif El-Refai hoped to become a leading authority in chemotherapy and its use in complex cases. Further he broadened his experience that included pharmaceutical practice and research, while aiding significant discoveries in the field of pharmacogenomics.
As an active member of the American Pharmacists Association (APhA), Sherif El-Refai holds additional certifications in immunization, anticoagulation, and advanced cardiovascular life support (ACLS). At ACLS classroom program they instructed the students in recognising both respiratory and cardiac arrest, iin additon to symptomatic bradycardia and other peri-arrest conditions. They also addressed early management strategies for these medical emergencies, as well as as airways management, and relevant pharmacology.
Additionally, the course assisted healthcare providers with respect to instances of strokes or acute coronary syndromes. Focusing on the importance of cooperation in cardiovascular life support, the educational program also helped to present strategies for effective communication and leadership while working with a resuscitation team.
A longtime clinical researcher with a wealth of experience in pharmacogenomics & individualized therapy Sherif El-Refai established his career as an ambitious medical professional in New Jersey. Graduated from the Eshelman School of Pharmacy at the University of North Carolina at Chapel Hill, he completed his clerkships on both coasts of the country by playing an active role in numerous outreach events.
Sherif El-Refai focused to serve the patient population of his local community while actively increasing his knowledge in the pharmaceutical industry. Since establishing his intrest in the medical field, Sherif El-Reafai has been passionate about all aspects of cancer treatment and hoped to become an expert in chemotherapy.
As an experienced pharmacist Sherif El-Refai futher pursued his PhD in pharmaceutical sciences at the University of Kentucky. Accomplished as an oncology pharmacist at the Markey Cancer Center, where he focused his research on lung cancer. In an order to make cancer treatment methods more successful he devoted his time and experience by donating to funds.
In his role role as an oncologist pharmacist Sherif El-Refai started researching on lung cancer, and even conducted Multidisciplinary Lung Cancer Program.The Lung Cancer Program also participated in clinical trials, which contributed to the discovery of new cancer treatments. In the terms to specialities at the Markey Caner Center he regularly treated patients with mesothelioma, bronchial carcinoid, esophageal cancer, and small- and non-small-cell lung cancer. With a team experts Sherif El-Refai utilized some of the latest advances in cancer treatment, from traditional radiation and chemotherapy regiments to the newest and most promising pharmaceuticals.
Sherif El-Refai is a PhD student at the University of Kentucky where he studies pharmaceutical sciences with a focus on clinical and experimental therapeutics. An experienced clinical researcher, Sherif El-Refai currently serves as an oncology pharmacist at the University of Kentucky’s Markey Cancer Center.
The Markey Cancer Center is a healthcare and research institution that has been providing cancer treatment for more than two decades. The center, which is in Lexington, Kentucky, offers innovative technology and high-quality, individualized patient care provided by a team of leading cancer specialists. In addition, the center operates wellness programs such as the Cancer Screening Program.
The Cancer Screening Program operates in partnership with education programs, research groups, and healthcare providers to offer comprehensive cancer prevention and screening services. Screenings, which are free for individuals who meet eligibility requirements, are available for lung, ovarian, prostate, skin, breast, cervical, and colorectal cancers. In addition, the American Cancer Society collaborates with the Markey Cancer Center to provide recommendations related to screenings. For more information on the program, visit www.ukhealthcare.edu/markeypatients-families/cancer-screening/.
In pursuit of a PhD in pharmaceutical sciences at the University of Kentucky College of Pharmacy, Sherif El-Refai also serves as an oncology pharmacist at the university’s Markey Cancer Center. As part of the Black Lab at the College of Pharmacy, Sherif El-Refai researches the ways in which gene expression affects patient responses to cancer treatments.
Under the leadership of researcher J. Julius Zhu, associate professor of pharmacology, a research team at the University of Virginia School of Medicine has created a new technique that lets scientists more quickly assess gene mutations and their effect. The technique uses lentivirus, a form of retrovirus similar to the human immunodeficiency virus (HIV), which replaces normal genes with mutated versions.
The technology allows scientists to assess the effect of each mutation on the body. It is more time and cost efficient than currently available methods of studying gene mutation, and thus will be more accessible to the typical research laboratory. With this new technology, research that would have once taken 10 years will take only three months.
Dr. Zhu has suggested that this advancement will allow physicians to develop better customized treatments. By identifying the type and nature of a gene mutation, physicians may be able to suggest interventions that are likely to generate the proper level of gene activity.